The Collection annually welcomes dozens of school groups and their teachers to learn about ancient Mesopotamia through first-hand experience with tablets and other objects. Students often try rolling cylinder seals and making cuneiform signs by writing with a stylus on clay. In addition, the Collection often hosts Yale undergraduate and graduate student classes, especially in the humanities and social sciences.

In 2013, a grant from MIT supported the production of a video for teaching early mathematics to high school students, using tablets from the Collection.

Third-millennium footstool (YBC 2467).